Our beleaguered musician is close to the open door and we hear him more clearly than before. Think of this degree of isolation as a doorway separating the noisy crowd (our computer). USB 3.0 adds mechanism for devices to send a Bus Interval Adjustment Message that is used by the host to adjust its 125 s bus interval up to +/-13.333 s. A device driver may change the interval with small finite adjustments depending on the implementation of host and system software. A USB hub, like the Regen, offers a degree of isolation between the computer and the DAC, though it’s not complete. USB 2.0 transmits SOF/uSOF at fixed 1 ms/125 s intervals. In fact, the idea of a purpose built USB hub is what the famous Uptone Regen essentially does – and it works well – improving audio in every case. While it may seem counter intuitive to improve something by adding another element in the data path, it works. One trick you can use is to connect the computer through a USB hub, using two USB cables–one between the computer and the hub, the other between the hub and the DAC. It’s near impossible unless you separate him from the crowd.

Think of your computer like a noisy crowd and the music like a lone musician trying to be heard at a cocktail party.

This is because your computer is a hostile environment for delivering clean audio data. 'When you connect your computer to your DAC through USB there’s a lot of problems getting the sound right. I get Paul McGowan's (Prez of PS Audio) daily email - Paul's Post - find it often interesting.

Usb 2 vs usb 3 dac